If prompted, log-in with your DePaul credentials (you may not need to do this if you're in your office on campus).
Steps 1-3 are sufficient to access Reaxys remotely. However, if you want to use the Predictive Retrosynthesis tool, you must activate the personalization feature. The only information shared with the vendor is your name and DePaul email -- your password is not shared. (This is possible because of OpenAthens, our federated authentication system.)
Your name should appear in the top right corner of the Reaxys screen. In the future, you'll just need to follow Steps 1-3 and you'll be automatically logged in and have full access to the tool and saved searches features.